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Draft

11.4.1 Primary endpoint

In the full analysis set, 412 participants were randomised1, and 96% completed the 24-week treatment period2.

The primary endpoint was met: 40% of participants on the study drug responded at week 243, against 21.6% on placebo3, as prespecified in the statistical analysis plan4.

Discontinuation for adverse events was low in both arms (3.1% and 2.4%)2.

Sources
✓1 Participant dispositionTable 14.1.1 · p. 188
✓2 Treatment completionTable 14.1.3 · p. 191
!3 Response at week 24The table reports 38.2%, not 40%.Table 14.2.1 · p. 212
✓4 Statistical analysis planSection 9.3 · p. 41
5 supported1 needs review

Illustration. The study and its numbers are made up.

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From sources to a document you can stand behind.

In this work, a document is accepted because people trust the chain from source to sentence. Dayton keeps that chain for every claim.

01

Bring the sources

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02

Draft against them

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03

Check every claim

Each number and sentence is checked against its source. A claim that overstates the evidence is flagged, not smoothed over.

04

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Why Dayton
Fluent drafts are easy.
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Checked

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